MHE513 - Risk Assessment and Epidemiology Module 5 - Case Essay

MHE513 - Risk Assessment and Epidemiology Module 5 - Case - Essay ExampleThe metals such as zinc, manganese, iron, fluoride ar considered as hepatotoxic non-carcinogens. Whereas chromium, ethylene bromide are considered as toxic carcinogens. The major difference between these two is that the toxic carcinogens will advert and alter the cells from its genetic level. Whereas the toxic non carcinogens will affect only the structure of the cells. The carcinogenic chemical substances have the capability to induce the mutagenic activity in the cells. These chemical reach the human body through inhalation and by dermal contact. The chemicals that gives rise to toxic endpoints other than cancer and gene mutations are called as overbearing toxicants because these toxins will affect only the organs of the system at a lethal dose or due to continuous characterisation to these chemicals. (Asante-Duah, 2002). For umteen toxic non carcinogens there are many protective mechanisms and treatment methods to overcome the toxicity, before it becomes severe. Whereas, the exposure to the carcinogens will create toxicity which is usually not recoverable. Even the down in the mouth exposure to carcinogens has severe effects. The toxicity parameters of non-carcinogenic chemicals are based on the acceptable daily intake (ADI). ADI is the amount of chemical (in mg/ kg body angle/day) to which a receptor can be exposed to on a daily basis over an extended period of time. (Asante-Duah, 2002). The toxicity parameters of the carcinogenic chemicals are based on the sensitivity of the sub population. The carcinogenic effect can be seen at the first exposure or even after many years of continuous exposure. Moreover the uncertainty factors are heavy for carcinogens than for non-carcinogens. Hence the communication of the risk to the people differs for the two types.Though for both the carcinogenic and non-carcinogenic chemicals the handling, the exposure levels, the